Volume 3, Issue 2 (3-2018)                   J. Hum. Environ. Health Promot. 2018, 3(2): 80-86 | Back to browse issues page


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Firouzkouhi Moghaddam M, Rakhshani T, Kadkhodaie F, Rashki M. Methadone and Buprenorphine for the Treatment of Opiate Addiction. J. Hum. Environ. Health Promot.. 2018; 3 (2) :80-86
URL: http://zums.ac.ir/jhehp/article-1-147-en.html
1- Research Center for Health of Adolescents and Children, Zahedan University of Medical Sciences, Zahedan, Iran.
2- Nutrition Research Center , School of Health , Shiraz University of Medical Science ,Shiraz , Iran.
3- Department of Public Health , School of Health, Mashhad University of Medical Sciences, Mashhad, Iran.
Abstract:   (697 Views)
Background: The rate of drug dependence and abuse is a growing problem in the Iran, number of opioid – dependent people is estimated at a total of 2000.000-4000.000 individuals. The aim of this study was a Comparison of Methadone and Buprenorphine in the Treatment of Opiate Addiction referring to a treatment clinic of Baharan psychiatric hospital in Zahedan city.
Methods: In a cross sectional study, 152 patients with opioid dependence were assigned into two treatment groups i.e. Methadone and Buprenorphine. Data were collected from patients using a questionnaire COWS. ANOVA and repeated measures regressions were used to evaluate the significant differences on using drug (methadone and Buprenorphine), time, and drug-by-time interaction terms.
Results: Patients on MMT and BMT differed in terms of Age started addiction (p = 0.0001); education level (p = 0.0001); and income (p = 0.0001), and no differed in term of sex (p =0.8). There was no significant difference between the two groups taking buprenorphine and methadone (Sig=0.87).
Conclusion: In conclusion, our study indicated, Buprenorphine and methadone are both proven to be effective treatment options.
Full-Text [PDF 755 kb]   (125 Downloads)    
Type of Study: Research Article | Subject: Special
Received: 2017/12/10 | Accepted: 2018/02/17 | Published: 2018/03/21

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