Volume 4, Issue 2 (6-2018)                   J. Hum. Environ. Health Promot. 2018, 4(2): 50-54 | Back to browse issues page

XML Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Yousefi Z, Rezaeigolestani M, Hashemi M. Biological Properties of Olive Oil. J. Hum. Environ. Health Promot.. 2018; 4 (2) :50-54
URL: http://zums.ac.ir/jhehp/article-1-170-en.html
1- Agricultural Engineering Research Group, Gilan Agricultural and Natural Resources Research and Education Center, AREEO, Rasht, Iran.
2- Department of Food Hygiene, School of Veterinary Medicine, University of Tehran, Tehran, Iran.
3- Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Abstract:   (283 Views)
Background: This review tries to explain various biological properties of olive oil.
Methods: In present review, data were obtained via a complete search through online databases including PubMed, Google Scholar, SID and ScienceDirect to find the relevant titles and paper abstracts using keywords like ‘olive oil’, ‘biological effect’ or ‘therapeutic’ or ‘food’. The obtained articles have been reviewed to evaluate different biological and therapeutic properties of olive and its edible products.
Results: Olive fruit and oil and the products obtained from olive tree (e.g., olive leaf extract) have unique medicinal properties. Studies have confirmed the positive effects of olive oil on wound healing, pain relief, cancer treatment, stroke, and cardiovascular diseases. In addition to the sensory properties of olive oil, the consumption of olive oil in the daily diet could enhance the safety and quality of food through antimicrobial and antioxidant compounds.
Conclusion: Considering the unique and significant medicinal and nutritional benefits of olive oil, it is necessary to encourage people toward the consumption of olive oil and increase their awareness about the importance and advantages of this product.
Full-Text [PDF 479 kb]   (122 Downloads)    
Type of Study: Review Article | Subject: Public Health
Received: 2018/05/7 | Accepted: 2018/06/3 | Published: 2018/06/20

1. Keshavarz S, Keshavarz M, Arab J. A Comprehensive Guide to Extra Virgin Olive Oil. Salian; 2017. p. 464. [In Persian].
2. Peri C. The Extra-virgin Olive Oil Handbook. Wiley Blackwell; 2014. [Crossref]
3. Vogel P, Kasper Machado I, Garavaglia J, Zani VT, de Souza D, Morelo Dal Bosco S. Polyphenols Benefits of Olive Leaf (Olea Europaea L) to Human Health. Nutr Hosp. 2014; 31(3): 1427-33.
4. Khalatbary AR, Ahmadvand H. Neuroprotective Effect of Oleuropein Following Spinal Cord Injury in Rats. Neurol Res. 2012; 34(1): 44-51. [Crossref]
5. Bisignano G, Tomaino A, Cascio R Lo, Crisafi G, Uccella N, Saija A. On the In-vitro Antimicrobial Activity of Oleuropein and Hydroxytyrosol. J Pharm Pharmacol. 2010; 51(8): 971-4. [Crossref]
6. Kyriazis ID, Koutsoni OS, Aligiannis N, Karampetsou K, Skaltsounis A-L, Dotsika E. The Leishmanicidal Activity of Oleuropein is Selectively Regulated Through Inflammation- and Oxidative Stress-related Genes. Parasit Vectors. 2016; 9(1): 441. [Crossref]
7. Ahmed AM, Rabii NS, Garbaj AM, Abolghait SK. Antibacterial Effect of Olive (Olea europaea L.) Leaves Extract in Raw Peeled Undeveined Shrimp (Penaeus semisulcatus). Int J Vet Sci Med. 2014; 2(1): 53-6. [Crossref]
8. Liu Y, McKeever LC, Malik NSA. Assessment of the Antimicrobial Activity of Olive Leaf Extract Against Foodborne Bacterial Pathogens. Front Microbiol. 2017; 8: 113. [Crossref]
9. Brenes M, Medina E, Romero C, De Castro A. Antimicrobial Activity of Olive Oil. Agro Food Ind Hi Tech. 2007; 18(4): 6-8.
10. Furneri PM, Marino A, Saija A, Uccella N, Bisignano G. In Vitro Antimycoplasmal Activity of Oleuropein. Int J Antimicrob Agents. 2002; 20(4): 293-6. [Crossref]
11. Shakarami Z, Dalireg N, Sheikhian A, Chehari K, Alirezaei M. Antioxidant and Immunomodulatory Effects of Olive Leaf Extract on Th17-Related Cytokines. Yafteh. 2005; 17(3): 67-77. [In Persian].
12. Alirezaei M, Dezfoulian O, Kheradmand A, Neamati S, Khonsari A, Pirzadeh A. Hepatoprotective Effects of Purified Oleuropein from Olive Leaf Extract against Ethanol-induced Damages in the Rat. Iran J Vet Res. 2012; 13(3): 218-26.
13. Abaza L, Taamalli A, Nsir H, Zarrouk M. Olive Tree (Olea europeae L.) Leaves: Importance and Advances in the Analysis of Phenolic Compounds. Antioxidants. 2015; 4(4): 682-98. [Crossref]
14. Stoneham M, Goldacre M, Seagroatt V, Gill L. Olive Oil, Diet and Colorectal Cancer: An Ecological Study and a Hypothesis. J Epidemiol Community Health. 2000; 54(10):756-60. [Crossref]
15. Fabiani R, De Bartolomeo A, Rosignoli P, Servili M, Montedoro GF, Morozzi G. Cancer Chemoprevention by Hydroxytyrosol Isolated from Virgin Olive Oil Through G1 Cell Cycle Arrest and Apoptosis. Eur J Cancer Prev. 2002; 11(4). [Crossref]
16. Diegelmann RF, Evans MC. Wound Healing: an Overview of Acute, Fibrotic and Delayed Healing. Front Biosci. 2004; 9: 283-9. [Crossref]
17. Sewall GK, Robertson KM, Connor NP, Heisey DM, Hartig GK. Effect of Topical Mitomycin on Skin Wound Contraction. Arch Facial Plast Surg. 2003; 5(1): 59-62. [Crossref]
18. Gurfinkel R, Palivatkel-Naim M, Gleisinger R, Rosenberg L, Singer AJ. Comparison of Purified Olive Oil and Silver Sulfadiazine in the Treatment of Partial Thickness Porcine Burns. Am J Emerg Med. 2012; 30(1): 79-83. [Crossref]
19. Vakilian K, Atarha M, Bekhradi R, Ghebleh F, Hatami Z, Ceraj A. The Effect of Lavender in Care of Postpartum Episiotomy Wounds. Shahrekord Univ Med Sci. 2008; 10(3): 63-9.
20. Cunningham FG, Leveno KJ, Bloom SL, Hauth JC, Gilstrap LC. Williams’s Obstetrics. 22nd ed. New York: McGraw Hill; 2005. p. 124.
21. Johnson JJ. Carnosol: A promising Anti-cancer and Anti-Inflammatory agent. Cancer Lett. 2011; 305(1):1-7. [Crossref]
22. Nussmeier NA. A Review of Risk Factors for Adverse Neurologic Outcome after Cardiac Surgery. J Extra Corpor Technol. 2002; 34(1): 4-10.
23. Harrison D, Griendling KK, Landmesser U, Hornig B, Drexler H. Role of Oxidative Stress in Atherosclerosis. Am J Cardiol. 2003; 91(3): 7-11. [Crossref]
24. Battino M, Quiles JL, Huertas JR, Ramirez-Tortosa MC, Cassinello M, Mañas M, et al. Feeding Fried Oil Changes Antioxidant and Fatty Acid Pattern of Rat and Affects Rat Liver Mitochondrial Respiratory Chain Components. J Bioenerg Biomembr. 2002; 34(2): 127-34. [Crossref]
25. Cho J, Kang JS, Long PH, Jing J, Back Y, Chung K-S. Antioxidant and Memory Enhancing Effects of Purple Sweet Potato Anthocyanin and Cordyceps Mushroom Extract. Arch Pharm Res. 2003; 26(10): 821-5. [Crossref]
26. Castagné V, Rougemont M, Cuenod M, Do KQ. Low Brain Glutathione and Ascorbic Acid Associated with Dopamine Uptake Inhibition during Rat’s Development Induce Long-term Cognitive Deficit: Relevance to Schizophrenia. Neurobiol Dis. 2004; 15(1): 93-105. [Crossref]
27. Rabiei Z, Bigdeli M, Mohagheghi F. Effect of Dietary Virgin Olive Oil on Infarct Volume and Brain Ceramide, Cerebroside and Phosphatidylcholine Levels in Rat Stroke Model. Shahrekord Univ Med Sci. 2013; 15(1): 23-31.
28. Beauchamp GK, Keast RSJ, Morel D, Lin J, Pika J, Han Q, et al. Ibuprofen-like Activity in Extra-virgin Olive Oil. Nature. 2005; 437: 45. [Crossref]
29. Huang Z-R, Lin Y-K, Fang J-Y. Biological and Pharmacological Activities of Squalene and Related Compounds: Potential Uses in Cosmetic Dermatology. Molecules . 2009; 14(1): 540-54. [Crossref]
30. Shabrandi S, Yousofvand N, Zarei F. Effect of Dietary Virgin Olive (Olea europaea (Oil on Nociception and Its Effect on Morphine-induced Analgesia in Male Mice Using Formalin Test. Iran J Nutr Sci Food Technology. 2016; 11(1): 43-50.
31. Pagidipati NJ, Gaziano TA. Estimating Deaths from Cardiovascular Disease: A Review of Global Methodologies of Mortality Measurement. Circulation. 2013; 127(6): 749-56. [Crossref]
32. Menendez JA, Papadimitropoulou A, Vellon L, Lupu R. A Genomic Explanation Connecting “Mediterranean diet”, Olive Oil and Cancer: Oleic Acid, the Main Monounsaturated Fatty Acid of Olive Oil, Induces Formation of Inhibitory “PEA3 transcription factor-PEA3 DNA binding site” complexes at the Her-2/neu (erbB-2. Eur J Cancer. 2006; 42(15): 2425-32. [Crossref]
33. Faine LA, Diniz YS, Galhardi CM, Rodrigues HG, Burneiko RC, Santana LS, et al. Synergistic Action of Olive Oil Supplementation and Dietary Restriction on Serum Lipids and Cardiac Antioxidant Defences. Can J Physiol Pharmacol. 2004; 82(11): 969-75. [Crossref]
34. Geelen MJH, Beynen AC. Consumption of Olive Oil has Opposite Effects on Plasma Total Cholesterol and Sphingomyelin Concentrations in Rats. Br J Nutr. 2007/03/09. 2000;83(5):541–7.
35. Nagyova A, Haban P, Klvanova J, Kadrabova J. Effects of Dietary Extra Virgin Olive Oil on Serum Lipid Resistance to Oxidation and Fatty Acid Composition in Elderly Lipidemic Patients. Bratisl Lek Listy. 2003; 104(7-8): 218-21.
36. Gu K, CC C, MI H. Diabetes and Decline in Heart Disease Mortality in us Adults. JAMA. 1999; 281(14): 1291-7. [Crossref]
37. Duntiz M. Diabetes and Lipids. 2nd ed. Maryland: PD Reck – less; 2001. p. 8-9.
38. Armin S, Taleban F, Tahbaz F, Mehrabi Y, Kamali Z. Comparison of the Effects of Consuming Olive and Sunflower Oils on the Fasting and Postprandial Blood Glucose Level and Lipid Profile in Type 2 Diabetic Female Patients. Iran J Nutr Sci Food Technology. 2010; 4(4): 75-8.
39. Lucas L, Keast AR and R. Molecular Mechanisms of Inflammation. Anti-Inflammatory Benefits of Virgin Olive Oil and the Phenolic Compound Oleocanthal [Internet]. Current Pharmaceutical Design. 2011. Vol. 17 p. 754-68. [Crossref]
40. Gilani AH, Shah AJ, Ghayur MN, Majeed K. Pharmacological Basis for the Use of Turmeric in Gastrointestinal and Respiratory Disorders. Life Sci. 2005; 76(26): 3089-105. [Crossref]
41. Kocic B, Filipovic S, Nikolic M, Petrovic B. Effects of Anthocyanins and Anthocyanin-rich Extracts on the Risk for Cancers of the Gastrointestinal Tract. J B.U.ON. 2011; 16(4): 602-8.
42. Bulotta S, Celano M, Lepore SM, Montalcini T, Pujia A, Russo D. Beneficial Effects of the Olive Oil Phenolic Components Oleuropein and Hydroxytyrosol: Focus on Protection against Cardiovascular and Metabolic Diseases. J Transl Med. 2014; 12(1): 219. [Crossref]

Add your comments about this article : Your username or Email:

Send email to the article author

© 2019 All Rights Reserved | Journal of Human, Environment and Health Promotion

Designed & Developed by : Yektaweb