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Showing 3 results for Pezeshki

Behnam Mohammadi-Ghalehbin, Ali Pezeshki, Mohammad Hasan Kohansal, Ghodsie Esmaeilnezhad,
Volume 2, Issue 2 (3-2017)

Background: Despite continued and comprehensive planning of the world health organization (WHO), intestinal parasitic infections are a serious public problem in developing countries. Due to the high prevalence of cancers in Ardabil province and subsequently the high possibility of intestinal parasitic infections among the people, the aim of this study was to assess the frequency of intestinal parasites in patients with malignancy in this area.

Methods: In this cross-sectional study, 100 fecal samples were collected from patients with cancer during February to September 2015. The specimens were examined for intestinal parasites using direct smear, formol-ethyl acetate concentration, agar plate culture and Ziel-Neelsen staining technique.

Results: The overall frequency of intestinal parasitic infections in studied cancer patients was 10%. The infection rates of detected intestinal parasites were Cryptosporidium spp. oocyst 4%, Blastocystis hominis 3%, Giardia lamblia 2% and Taenia spp. 1%.

Conclusion: Despite the low frequency of intestinal parasites, there is a need to screen cancer patients for some important parasitic infections such as Cryptosporidium spp. and Strongiloides stercoralis because of irreparable effects of those parasites on thepatients and to increase awareness among clinicians regarding the occurrence of parasitic infections in these patients.

Ali Pezeshki, Elnaz Kadkhodamohammadi, Abbas Mahmmodzadeh, Ali Haniloo,
Volume 2, Issue 3 (6-2017)

Background: The genus of Acanthamoeba is an opportunistic protozoan parasite with a worldwide distribution where it is able to cause fatal granulomatous amoebic encephalitis (GAE) and amoebic keratitis (AK). This organism inhabits in the wide range of natural and man-made aquatic environments. The present study was carried out to evaluate the presence of Acanthamoeba spp. in the various water resources of Zanjan province, northwest Iran, using both morphological and molecular methods.
Methods: The Water samples were randomly collected from 30 water sources in different parts of Zanjan, Iran, between April 2015 and May 2016. Then, the samples were cultured on non-nutrient agar and the Acanthamoeba genus identified by morphological characters. The polymerase chain reaction (PCR) was performed using the 18S rRNA gene as a molecular marker. 
Results: The obtained data showed that, out of the 60 water samples collected, 30 (50%) were positive for Acanthamoeba spp. According to morphological and molecular approaches.
Conclusion: The present investigation is the first report of the distribution of Acanthamoeba spp. in the various water sources of Zanjan province, gives baseline knowledge regarding water contamination with Acanthamoeba spp. in these areas and emphasizes the necessity of more attention to water sources in order to prevent infections associated with Acanthamoeba spp.

Ali Pezeshki, Ali Haniloo, Abbas Mahmoodzadeh, Parvin Farahmandian,
Volume 4, Issue 2 (5-2018)

Background: Genus Acanthamoeba belongs to free-living amoebae, which could pose risk to the central nervous system and cornea and is considered to be a significant health concern. The present study aimed to evaluate the presence of Acanthamoeba spp. in malignant patients in Zanjan, located in the northwest of Iran, using morphological methods.
Methods: Nasal specimens were collected from 100 malignant patients using swabs in the hospitals in Zanjan, Iran during July 2017-August 2018. The samples were cultured on non-nutrient agar, and the Acanthamoeba genus was identified based on the morphological characteristics.
Results: Based on the morphological features, six samples (6%) were positive for Acanthamoeba spp.
Conclusion: This was the first report on the presence of Acanthamoeba spp. in malignant they patients in Zanjan city, which provides further evidence on the existence of Acanthamoeba spp. The findings emphasize that special attention should be paid to immunocompromised patients in order to prevent the infections associated with Acanthamoeba spp.

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