Volume 23, Issue 97 (4-2015)                   J Adv Med Biomed Res 2015, 23(97): 112-121 | Back to browse issues page

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Sayehmiri K, Tavan H, Sayehmire F, Mohamadi I. Prevalence of Epilepsy in Iran Using Meta-Analysis and Systematic Review. J Adv Med Biomed Res. 2015; 23 (97) :112-121
URL: http://zums.ac.ir/journal/article-1-3094-en.html
Abstract:   (15914 Views)

Background and Objective: Epilepsy is a one of the most common diseases causing many problems in Iran. Hence, this study was an attempt to assess the prevalence of epilepsy using meta-analysis and systematic review methods in Iran. Materials and Methods: Nine Iranian papers published in time period of 2002 to 2010 were selected using valid keywords and searching in the SID, Google scholar, PubMed and Elsevier databases. The heterogeneity of samples was dealt with using the I2 index. Results: In this study, the data of 7723 patients was used and nine papers were selected for meta-analysis among the published papers. The total prevalence of epilepsy was calculated to be 5% (95% confident interval (CI): (2%-8%) in Iran. The prevalence of epilepsy in central, northern and eastern areas of Iran was found to be 5% (95% CI, 2%-8%), 1% (95% CI, -1%-3%) and 4% (95% CI, 3%-11%), respectively. Somatic diseases and inheritance were the common risk factors of epilepsy with the percentage of 39% (95% CI, 15%-62%) and 26% (95% CI, 9%-42%), respectively. Conclusion: The findings in our study indicated a 5% more prevalence of epilepsy in Iran until 2010 in comparison to similar countries though this trend decreased with increasing age. Geographic area evidence showed a remarkable prevalence in the Center, East and North of the country and physical illnesses comprised the major risk factors. References 1-Valizadeh L, Akbarbegloo M, Zamanzadeh V, Rahiminia E, Caleb Ferguson F. The relationship between psychosocial care and attitudes toward illness in adolescents with epilepsy. Epilepsy Behav. 2013 27: 267-71. 2- Papavasilion AS, Kotsalis C, Paraskevoulakos E, Karaqouis P, Pizou C, Baziqou H. Intravenous midazolam in convulsive status epilepticus in children with pharmacoresistant epilepsy. Epilepsy Behav. 2009 14: 661-4. 3- Pei-min Yu, Ding Ding G, Lan Xu, et al. 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A Comparison of Phenobarbital and Phenytoin Serum Levels between Children with Status Epilepsy and refractory status epilepsy. J Zanjan Univ Med Sci. 2007 15: 24-31. 9- Al-Rashed H, Al-Yahya D, Al-Kandari A, Al-Sabah R, Al-Taiar A. Knowledge of, perceptions of, and attitudes toward epilepsy among university students in Kuwait. Epilepsy Behav. 2009 14: 367-71 10- Schmidt D. Drug treatment of epilepsy: options and limitations. Epilepsy Behav. 2009 15: 56-65. 11- Kerling F, Pauli E, Lorber B, Blümcke I, Buchfelder M, Stefan H. Drug withdrawal after successful epilepsy surgery: how safe is it?, Epilepsy Behav. 2009 15: 476-80. 12- Hao XT, Wong IS, Kwan P. Interrater reliability of the international consensus definition of drug-resistant epilepsy: a pilot study. Epilepsy Behav. 2011 22: 388-90. 13- Mushia D, Burton K, Mtuya C, Gona JK, Walker R, Newton CR. Perceptions, social life, treatment and education gap of Tanzanian children with epilepsy: a Community-based study. Epilepsy Behav. 2012 23: 224-9. 14- Feldman AE, Gidal BE. Prolongation by antiepileptic drugs and the risk of torsade de pointes in patients with epilepsy. Epilepsy Behav. 2013 26: 421- 6. 15- Saz EU, Karapinar B, Ozcetin M, et al. Convulsive status epilepticus in children: etiology, treatment protocoland outcome. Seizure. 2011 20: 115-8. Jonathan H. McKinnon 16- Shareef YS, Mc Kinnon JH, Gauthier SM, Noe KH, Sirven JI, Drazkowski JF. Counseling for driving restrictions in epilepsy and other causes of temporary impairment of consciousness: how are we doing? Epilepsy Behav. 2009 14: 550-2. 17-Hosseinia N, Ahmadi F, Zare M. Striving for balance: coping with epilepsy in Iranian patients. Epilepsy Behav. 2010 18: 466-71. 18- Aydemir N, Trung DV, Snape D,Baker GA, Jacoby A. Multiple impacts of epilepsy and contributing factors: findings from anethnographic study in Vietnam. Epilepsy Behav. 2009 16: 512-20. 19- The global campaign against epilepsy. Geneva: World Health Organization 2000. 20- Scott RA, Sander. The treatment of epilepsy in developing countries: where do we go from here? Bull World Health Organ. 2001 79: 344-51. 21- WHO, 'International Bureau for Epilepsy, International League Against epilepsy.Atlas: Epilepsy Care in the World. Geneva: Who (2005). 22- Szaflarski M, Szaflarski JP, Privitera MD, Ficker DM, Horner RD. disparities in the treatment of epilepsy: what do we know? what do we need to know? Epilepsy Behav. 2006 9: 243-64. 23- Nachvak M, Rezaei M Haghighat HR, 'Prevalence and monitoring of retarded childs in Tehran at 2002. J Kermanshah Univ Med Sci. 2004 3: 34-42. 24- Pashapour A, Sadrodini A. Grandmal epilepsy and variations in primary school children at Tabriz. Med J Tabriz Univ Med Sci. 2001 50: 23-7. 25- Mohammadi MR, Ghanizadeh A, Davidian H, Mohammadi M, Norouzian M., Prevalence of epilepsy and comorbidity of psychiatric disorders in Iran. 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Type of Study: Clinical Trials |
Received: 2015/04/29 | Accepted: 2015/04/29 | Published: 2015/04/29

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