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Showing 2 results for Amirmoghadami

Na Mozafari, S Talaei, Hr Amirmoghadami, S Talaei,
Volume 14, Issue 55 (Jun 2006)

Background & Objectives: Chronic Otitis Media (COM) remains one of the most common childhood chronic infectious diseases worldwide. This study was carried out to determine the organisms inducing COM and their drug resistance patterns in Zanjan. Materials & Methods: This cluster cross-sectional study was conducted on 100 patients suffering from COM in the age range of 18-45. COM specimens were obtained in operating room and then cultured on 4 different media. Following the diagnostic tests and identifying the bacteria, their susceptibility to antibiotics was assessed. Results: The most common isolated bacteria were Pseudomonas aeruginosa (24.7%), Staph ylococcus aureus (17.6%) and Proteus spp (15.2%). The results of bioassay tests for isolated bacteria were as follows: Pseudomonas aeruginosa had the highest resistance to cefixime and co-trimoxazol (100%). The highest resistance of Staphylococcus Aureus was to co-trimoxazol (70%) and cefixime (50%). Conclusion: Regarding the multi-bacterial etiology of COM and high prevalence of antibiotic resistance, identification of causative bacteria and bioassay test prior to any therapeutic procedure seams necessary.

R Eghdam Zamiri, M Moghimi, N Mosavi Nasab, H Amirmoghadami, M Joghatae , A Feizi,
Volume 20, Issue 81 (9-2012)

Background and Objective: Elevation of the b-HCG serum levels has been reported in several tumors including breast cancer, and it is usually associated with aggressiveness. The aim of this study was to examine the possible correlation between the b-HCG serum levels and different grades of breast cancer tumors in patients undergoing chemotherapy. Materials and Methods: This cross-sectional study was conducted in the city of Zanjan during 2009-10. Serum samples from 56 cases of breast cancer patients were collected after surgery and prior to chemotherapy for analysis of total free b-HCG by electro chemiluminescence immunoassay, and the same procedure was repeated after 8 courses of chemotherapy. The b-HCG serum levels were compared in poor versus mild to moderate grades before and after chemotherapy. Results: In 37 cases of mild to moderate grade tumors, the mean b-HCG level was 1.09 ±1.4 miu/ml compared with 1.2 ±0.3 miu/ml (P= 0.75) in 29 cases of poor grade tumors. The mean b-HCG levels before and after chemotherapy were 1.15 ±1.4 miu/ml and 1.17 ±1.4 miu/ml (P=0.24), respectively. Conclusion: We did not find any significant association between the b-HCG serum levels and breast cancer tumor grades. Furthermore, chemotherapy does not appear to have an effect on b-HCG serum levels.

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