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Showing 42 results for Mohammadi

A Mohammadi, Ar Shoghli,
Volume 14, Issue 54 (Mar 2006)
Abstract

Background & Objective: Improving quality of hospital services helps to optimize resource utilization and promotes quality of care and community satisfaction. Since identification of staff perceptions and expectations leads to increased efficiency, improvement of organization products and fulfillment of customers' present and future needs, this research was conducted in order to analyse total quality management (TQM) elements in Zanjan's hospitals from 2003 through 2004. Materials & Methods: This descriptive study was carried out on 256 employees of different hospitals in Zanjan province who had been selected through stratified random sampling. Data collecting tool was questionnaire (Likert scale) including optimal situation (expectations) and present situation (perceptions) of TQM elements which was completed by research samples. The gap between expectations and perceptions was calculated by subtracting the perceptions scores from expectations score. The results were analysed through statistical test (Kroscal-Wallis Wilcoxon). Results: The mean gap scores between optimal situation (expectations) and present situation (perceptions) were significant in all elements of TQM (P=0.01). The fair recognition and reward system was the most important dimension from employees' standpoint and scored the most negative (mean gap score= -3). Quality culture and staff empowerment were rated as the second and third most important dimensions. Conclusion: The results indicate that fair recognition and reward system, the initiative and creative culture and staff empowerment are the most important preconditions of effective implementation of TQM in hospitals. Thus, it is recommended that hospital managers establish fair reward system based on well-done performance and encourage creative work and quality culture.


M Ghaemi, M Ansari, S Mohammadi,
Volume 14, Issue 56 (Sep 2006)
Abstract

Background & Objective: Outpatient surgery can be performed by general or spinal anesthesia. Spinal anesthetic drugs have side effects. Many anesthesiologists choose general anesthesia, because of its relative predictability and to avoid undesirable side effects associated with spinal anesthesia. For example lidocaine is frequently associated with Transient Neuroligic Symptoms (TNS). Bupivacaine may cause urinary retention, prolonged discharge time and unpredictable level of anesthesia dependent on dose. Reducing bupivacaine dose will shorten the duration of action and its anesthesia level will be predictable in saddle block technique. This study was designed to assess the effects of hyperbaric, low dose bupivacaine in level of sensory block, duration of anesthesia and selective sensory block in an rectal surgery and its comparison with lidocaine. Materials & Methods: In a clinical trial study, 64 patients who were the candidates for anorectal surgery were divided in two groups randomly. In one group, hyperbaric bupivacaine 0.5% was injected in sitting position. The other group received hyperbaric lidocaine 5% in the same position. The patients were laid in lithotomy position after 5 minute. Blood pressure, pulse rate, severity of sensory & motor block, duration of anesthesia and tonicity of anal sphincter were recorded in two groups. The results were analyzed through T-test, chi square and variance analysis. Results: Sensory level and anesthesia duration in bupivacaine group were higher than lidocaine group. Motor block degree and anal sphincter tonicity loss in lidocaine group were greater than the other one. Blood pressure decreasing in lidocaine group was significantly higher to bupivacaine group. Conclusion: The proper sensory level and short anesthetic duration of low-dose hyperbaric bupivacaine are comparable with lidocaine in saddle block position, and selective sensory block may be useful for anorectal surgery in lithotomy position.


S Mazloomzadeh, A Moosani, H DinMohammadi,
Volume 14, Issue 56 (Sep 2006)
Abstract

Background & Objective: The prevalence of obesity, one of the greatest public health problems in the world has tripled in many countries since three decades ago this increase is often faster in developing countries than in the developed world. Gathering information on the main factors involved in the occurrence of obesity in different geographical areas plays a key role in the prevention of it. Therefore, the aim of this study is to evaluate the prevalence of overweight and obesity in relation to various factors in the Zanjan population. Materials & Methods: This cross-sectional study was conducted on 2500 Zanjan residents aged between 15 and 64 years who were randomly selected through cluster sampling via their postal codes, using the protocol of the WHO STEPwise approach. Information on demographic characteristics was collected using questionnaires. Weight and height were measured according to standard protocols. Those with a BMI within the range of 25-29.9 Kg/m2 and 30 Kg/m2 or above were classified as overweigh and obese, respectively. Overweight and obesity were defined based on the WHO classification. Data was analyzed using Chi-Square tests and Logistic regression models to estimate odds ratios. Results: The prevalence of being overweight and obese in this population were 30.7% and 15% respectively. The proportion of obesity was 21.3% in women and 8.9% in men. The prevalence of obesity increased with increasing age and in both sexes was the highest in 45-54 year olds. Both prevalences of overweight and obesity were greater in urban residents and married participants. The prevalence of obesity was also decreased with increasing educational level. Conclusion: High prevalence of overweight and obesity in this population, specifically within high-risk groups, highlights the need to implement interventions for reducing this epidemic.


Mr Jafari, S GolMohammadi, F Ghasvand,
Volume 14, Issue 57 (Dec 2006)
Abstract

Background & Objective: ‎Cannabinoids have a dose-related antinociceptive effect in animals and humans through Cannabinoid receptors (CB1,CB2). Several ‎studies have suggested that CB2 receptors are not expressed in the CNS but others suggest that there are a few, although significant, receptors in that area. To date no studies have been done on the antinociceptive effect of central administration of a CB2 agonist. In this study the central and peripheral analgesic effect of JWH133 (a CB2 agonist) was examined.‎ Materials & Methods: Male mice were used in this study. The antinociceptive effects of intracerebroventricular (i.c.v.) administration of JWH133 ‎using formalin test was studied in stereotaxed mice after one week of ‎surgery and the insertion of a stainless steel cannula in the left cerebroventricle. To study peripheral effects of JWH133, the drug was administered intraperitoneally (i.p.). Results: The i.c.v injection of JWH133 had no effect but i.p. injection of the drug had analgesic effects. Conclusion: The present results may suggest that there are no any effective analgesic CB2 receptors in the CNS.


M Roghani, T Baluchnejadmojarad, M Fallah_ Mohammadi,
Volume 15, Issue 59 (6-2007)
Abstract

Background and Objective: Diabetes mellitus (DM) especially type A, is accompanied by disturbances in learning, memory, and cognitive skills in human society and experimental animals. Regarding the beneficial effect of SM on lipid peroxidation in hyperlipidemia and on serum lipids in DM, this study was conducted to evaluate the effect of prolonged oral administration of SM on learning and memory in diabetic rats. Materials and Methods: Female wistar rats (n = 36) were randomly divided into control, SM-treated control, diabetic, and SM-treated diabetic groups. Treatment groups received a mixture of SM and standard rat food at a weight ratio of 6.25% for 4 weeks.To induce diabetes, streptozotocin was injected intraperitoneally at a single dose of 60 mg/kg. For evaluation of learning and memory, initial latency (IL) and step-through latency (STL) were determined at the end of the study using passive avoidance test. Meanwhile, alternation behavior percentage was determined using Y maze test. Results: There was a significant increase (p = 0.032) in IL in diabetic and SM-treated diabetic groups after 4 weeks compared to control group. There was no significant difference between diabetic and SM-treated diabetic groups. On the other hand, STL decreased significantly (p = 0.032) in diabetic group while it increased significantly (p = 0.027) in SM-treated group compared to control group at the end of the study. The results of Y maze showed that alternation score was not different between treated and untreated diabetic groups. Conclusion: SM could enhance the consolidation and recall capability of stored information but did not affect spatial memory of diabetic animals.


Mr Din Mohammadi, K Amini, Mr Yazdan Khah,
Volume 15, Issue 59 (6-2007)
Abstract

Background and objective: Opioid addiction is a major social problem among all societies worldwide. According to official reports there are about 1,200,000 chronic addicts and 800,000 recreational consumers throughout the country. One of the perplexing problems regarding addiction is its relapse since 50% of rehabilitated Iranian addicts tend to reconsumption. The aim of this study is to determine the socicl and environmental factors related to the relapse of opioid addiction. Materials and methods: In this descriptive study 96 volunteer male addicts referring to rehabilitation center of welfare organization were selected through convenient sampling. The survey tool was the questionnaire whose validity and reliability had bean confirmed before the application. Data collecting wa carried out by two trained experts through structured interview within three months. The data was analysed using SPSS -Win software. Results: The results showed that the mean age of research population was 34.66 ± 8.52. All study cases had experienced at least one attempt to quit drug use. The investigation regarding the career factor showed that they believed lack of permanent job (51%), exhausting work conditions (42.7%), failure in career achievement (41.7 %) were the leading factors in relapse of opioids substance use. The addicts reported their viewpoints regarding the other factors as follows: cost of living burden (53.1%), educational factors ( poor literacy skills (33.3%), and illiteracy (19.8%). Among familial factors in singles, lack of appropriate family relations (43.7%), and in married addicts, marital discord (22.5%), and lack of proper interaction among family members (21.2%) were the major factors. Regarding the social factors convenient availability of opioids substance (85.4%), common use of opioids in public (80.2%), and association with addicted friends (70.8%) were the leading factors. Conclusion: the study results indicated that among investigated factors, social, occupational and economic factors rank the most important factors in relapse of opioid addiction. Accordingly, a few recommendations have been given.


A Oodi, R Halabian, M Mohammadipour, N Amirizadeh, M Amani, N Masroori, A Gharehbaghian, M Habibi Roudkenar,
Volume 15, Issue 60 (5-2007)
Abstract

Background and Objective: Rh (Rhesus) is a highly complex blood group system in man which plays an important role in transfusion medicine. The aim of this study was the isolation of RhD protein from the membrane of RBCs. Materials and Methods: In this experimental study immunoprecipitation method with human anti-RhD polyclonal antibody was utilized for the isolation of RhD antigen from Rh+ human blood samples Proteins of RBCs were characterized by SDS-PAGE and Western blot analysis. Antigenicity of the RhD protein was assessed by ELISA using commercially available human anti-RhD polyclonal antibody with peroxidase conjugated goat anti-human as a secondary antibody. Results: The results show that RhD protein has successfully been isolated by immunoprecipitation method. The expected size of RhD protein was confirmed by Western blot analysis. RhD antibody reacted with RhD antigen prepared from ghost with polyclonal antibody in ELISA, but no reaction was observed in Western blot analysis with monoclonal antibody: It is necessary to mention that this is the primary report of relative purification of RhD and further studies are recommended. Conclusion: The RhD may be helpful to further investigate the molecular basis of RhD protein and could be applicable for production of anti- D antibody in an animal model.


M Gholami, H Mohammadi, Sh Mirhosseini, A Ameri, Z Javadi,
Volume 15, Issue 61 (12-2007)
Abstract

Background and Objective: PACT is an adsorption- degradation process through which slowly or non-biodegradable waste water compounds such as dye can be degraded. This study was carried out to evaluate the efficacy of PACT in removal of dyes form textile industry wastewaters. Materials and Methods: This research was carried out in pilot scale. The pilot design had two parts: an aeration tank with 40L volume and a clarifier with 12L volume. The dyes used in this research were acid and reactive dyes in different concentrations which are mostly used in textile industries. First, the biodegradability of the dye was studied through Zahen-Wellens method (ISO 9888, 1999). Then, dye removal efficiency in different conditions of powdered-activated carbon concentration and operational conditions were evaluated. American Dye Manufacture Institute (ADMI) method was utilized for determination of dye removal in samples. Results: Biodegradability of acid dyes and basic dyes in 100 mg/L dye concentration, were 60 and 80% respectively. On the other hand, the best efficiency for application of PAC in activated sludge process, was obtained in 1500 mg/L PAC concentration. In this situation, with 30 hydraulic retention time, and 30oC temperature, the rejection percent of dye was 98.8%. Conclusion: PACT process could be the best method for removal of different dyes used in textile industry with high efficiency (up to 90%). Application of this method in treatment of textile wastewaters is an important economic improvement, which in a single step, allows the removal of COD and color from textile wastewater without additional physicochemical treatment.


S Nasseri, R Sorouri Zanjani, Z Pourpak, N Rezaei, M Moin, N Parvaneh, A AghaMohammadi,
Volume 16, Issue 64 (9-2008)
Abstract

Correlation of Null Btk Expression and Gene Noncoding Mutations in XLA Patients Nasseri S1, Sorouri R2, Pourpak Z3, Rezaei N4, Moin M5, Parvaneh N6, Aghamohammadi A7 1 Dept of Molecular Biology, Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran 2 Baqiyatallah University of Medical Sciences, Tehran, Iran and, Zanjan University of Medical Sciences, Zanjan, Iran 3 Dept of Immunology, Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran 4 Dept of Immunology, Immunology, Asthma and Allergy Research Institute and Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran 5 Dept of Immunology, Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, Iran 6 Dept of Infectious Diseases, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran 7 Section of Immunology and Allergy, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran Corresponding Author's Address: Section of Immunology and Allergy, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran E-mail: aghamohammadi@sina.tums.ac.ir Received: 20 July, 2008 Accepted: 29 Dec, 2008 Background and Objective: X-linked agammaglobulinemia (XLA) is a primary immunodeficiency disorder characterized by recurrent bacterial infections, profound lack of serum antibodies and reduced circulating B lymphocytes. Mutations in Bruton´s tyrosine kinase gene (BTK) result in XLA. It is shown that absence of Btk protein expression may be accompanied by no mutations in coding regions in some cases, instead alterations in conserved regulatory domains of promoter and the first intron of BTK gene maybe occurred. The aim of this study was evaluation of Btk expression and mutation analysis in coding and regulatory regions of the gene. Materials and Methods: In this study, eleven XLA patients were enrolled. Btk expression was analyzed by western immunoblotting method. Mutation analysis was carried out in eight patients. In three cases, PCR of the regulatory regions was performed with designed primers, followed by sequencing. Results: According to western blot, normal Btk expression in three patients and null expression in eight others was observed. Mutation analysis showed two novel BTK mutations in two patients (1038-1040 delAGG and IVS8-2delA). No coding or regulatory region mutations were found in three cases with null Btk expression. Conclusion: Based on these results, three cases with null expression and had no coding or regulatory region mutations are interesting. It is possible that some rare regulatory defects may have been occurred, other than conventional sites. This must be taken into account for future investgations.


A Mohammadi, Ar Shoghli,
Volume 16, Issue 65 (12-2008)
Abstract

Background and Objective: Among service organizations, health care sector has an important role, because it has the mission of maintaining community well-being. Thus, delivery of high quality health services is essential and should be appropriate with professional standards. Communal understanding of quality concepts helps organization to focus on quality improvement efforts. In addition, understanding of clients’ expectations and perceptions of services quality is one of the first requirements for improving quality of health services. This study was designed to evaluate the quality of health services in Zanjan district health centers based on clients’ expectations and perceptions and to determine the strengths and weaknesses of primary health cares. Materials and Methods: In this cross-sectional study, a self-administered SERVQUAL questionnaire was used for data collection. A total of 300 femaleُs of the health care consumers were selected through random clustering sampling and completed the related questionnaire. The statistical analysis was performed using appropriate software. Results: The results indicated that the health service quality was not concordant with the clients’ expectations and perceptions in all relevant dimensions. Expectations exceeded the perceptions in all dimensions of services quality. Mean score of overall service quality was (-1/22) (p < 0.0001). The reliability dimension (ability to provide the promised service and accurately) was rated as the most important service (-1/13). The lowest mean score (-1/13) belonged to the tangible dimension (p < 0.0001). Conclusion: The results of this study showed that the reliability dimension constitutes the most serious problem facing district health centers. It is recommended that responsible employees and physicians should provide the promised services on time accurately and keep the records of services provided to clients without mistake. It further confirmed that the SERVQUAL elements can help health centers for defining the important areas of services and improving them. Keys word: Services quality, SERVQUAL, Expectations, Perceptions, Zanjan


M Golami, H Mohammadi, Sa Mokhtari,
Volume 17, Issue 68 (9-2009)
Abstract

Background and Objective: Arsenic (As) is a highly toxic metalloid found in ground and surface waters. Arsenic contamination in drinking water leads to harmful effects on human health. In this study, the efficacy of Reverse Osmosis (RO) membrane technology was evaluated for arsenic removal from drinking water. Materials and Methods: This experimental study was carried out on RO membrane spiral- wound module (model: 2521 TE, CSM Co. Korea) in pilot scale. After preparation of sodium arsenate solution in the laboratory, performance of RO membrane system in arsenic (As) removal was investigated. Experiments were conducted with five different pressures (100, 130, 160, 190, 210 Psi), pH (4, 5.5, 7, 8.5, 10), temperature (20, 25, 30, 35, 40°C) and an initial As concentration of 0.2 mg/L. The influence of different feed concentrations (0.2, 0.5, 1, 1.5, 2 mg/L) on As removal efficiency was also examined. In each step, flux was measured and after 30 minutes samples were taken. Arsenic amount in feed and permeate were measured by silver diethyldithiocarbamate (AgDDTC) method. Results: The results of this study demonstrated that greater than 90% of As can be eliminated from drinking water. Also the results showed that the pressure of 190 psi, As concentration of 0.2-0.5mg/L, temperature of 25-300C and pH = 6-8 were the optimal conditions. Conclusion: Arsenic removal efficiency in optimal conditions of system performance was up to 99%.


M Ganjkhani, K Moradi, S Ramezani, F MirzaMohammadi, A Fallah,
Volume 18, Issue 70 (3-2010)
Abstract

Background and Objective: Epileptic seizures are generally considered as complex and abnormal hyperexcitable phenomena in the brain. Probable changing of excitability in visual cortex by dark rearing (DR) might lead to clonic seizure. In this study the possible effect of dark rearing on Pentylenetetrazol (PTZ) - induced generalized clonic seizure was studied. Materials and Methods: To assess the generalized clonic seizure (GCS) threshold and incidence and latency of GCS, 0.5% Pentylenetetrazol was administrated intravenously and 80 mg/kg subcutaneously to the control and dark reared animals. Results: Our results showed that generalized clonic seizure threshold in DR group was not changed but occurring of GCS in DR animals was significantly lower and its latency was higher than the control animals. The tonic – clonic seizure was not different between the two groups. Conclusion: In spite of increasing seizure susceptibility in visual cortex by light deprivation, a kind of protection was observed in dark reared animals. Further studies seem to be necessary to elucidate the role of other factors such as melatonin.


S Mohammadi, Mj Hasseinzadeh Attar, M Karimi, A Hossainnezhad, Mr Eshraghian, Sh Hosseini, M Rahmani, A Karimi, N Jafari,
Volume 18, Issue 70 (3-2010)
Abstract

Background and Objective: Adiponectin is a novel adipose tissue-specific adipokine that can increase insulin sensitivity. Many studies have shown anti obesity and anti diabetic effects of green tea consumption. In this study we examined the effects of green tea extract on circulating adiponectin levels and insulin resistance status in patients with type 2 diabetes mellitus (T2DM). Materials and Methods: In this double blind randomized clinical trial 58 type 2 diabetic patients with BMI ≥ 25 were recruited from an unselected population from the outpatient clinic of Shariati Hospital, Tehran, Iran. Patients were randomly divided into two groups green tea extract and placebo. All the patients received the capsules for 8 weeks. Laboratory measurements including fasting serum adiponectin, insulin, HOMA-IR, FPG, OGTT, HbA1c and lipid profile and anthropometric were performed before and after the intervention. Nutrient intakes were obtained via 24- hour recall from each patient in three successive days. The data were analyzed using appropriate software. Results: We found a significant effect of green tea extract on increasing the logarithm of serum adiponectin in diabetic patients (0.15±0.10 µg/ ml, P < 0.05). A significant independent correlation between the logarithm of serum adiponectin and WHR (Waist to Hip Ratio) was found (P= 0.009, t= -2.7). The consumption of green tea extract had a significant effect in control the levels of HbA1C, weigh and also BMI in green tea group (P < 0.05). Conclusion: The results showed that consumption of green tea extract can be useful in the control of T2DM by increasing the levels of serum adiponectin and controlling the weight, BMI and HbA1C levels in patients with T2DM.


S Rabie Siahkali, Mh Pourmemari, T Khaleghdoost Mohammadi, F Askandari, A Avazeh,
Volume 18, Issue 70 (3-2010)
Abstract

Background and Objective: Hospitalization of a family member especially in the intensive care units (ICUs) is a crisis that can cause anxiety in the whole family. The present study was conducted to determine some effective factors that can lead to anxiety in families of patients hospitalized in Rasht ICUs in 2006. Materials and Methods: In this cross–sectional study 218 family members of 130 inpatients of Rasht Poorsina and Razi hospital ICUs were selected. Data were collected using researcher–made and hospital anxiety depression (HADS) questionnaires. Results: The results showed that the majority (77.1%) of patients’ family members were anxious. The anxiety odd ratio (OR) by logistic regression showed that anxiety rate increased with the decrease of patients’ consciousness level (OR= 9.726 per additional point), family members’ sex (OR= 6.171), making decision by family members (OR= 6.433) and older age (OR= 0.939 per additional year). Conclusion: The results confirmed the role of several important factors in inducing anxiety to the ICU inpatients’ families which require further consideration. These factors are recommended to be investigated upon admission and provide nursing care for preventing and overcoming anxiety in both patients and families.


M Gholami, R Mirzaei, H Mohammadi,
Volume 19, Issue 74 (3-2011)
Abstract

Background and Objective: In this research, landfill leachate treatment in Karaj city was investigated by a linked septic tank and aerated lagoon. Materials and Methods: At first, characteristics of the leachate were determined. Then a pilot plant with anaerobic-aerobic (Septic tank and Aerated lagoon) parts was installed and started. Results: Results showed that Chemical Oxygen Demand (COD) removal efficiency for septic tank and subsequently to lagoon for influent COD of 19537 mg/L, were 8401 and 432 mg/L, respectively. The septic tank and aerated lagoon also operated with different flow rates and the best results for septic tank and aerated lagoon obtained in 23.6 L/day and 9.3 L/day respectively with maximum COD removal efficiency of 91.2%. Conclusion: According to the obtained results, the hybrid system had 90% COD removal efficiency. Therefore, leachate COD loading could be effectively removed in this system.


V AghaMohammadi, B Pourghassem Gargari, A Aliasgharzadeh,
Volume 19, Issue 76 (5-2011)
Abstract

Background and Objective: In patients with diabetes, elevated homocysteine levels have been reported to be associated with endothelial dysfunction, insulin resistance, dyslipidemia, poor control of disease, nephropathy, macroangiopathy and oxidative stress. Thus, this observational study was performed to determine the plasma homocysteine level and its correlation with clinical, biochemical and nutritional variables. Materials and Methods: This study was performed on 70 men with type 2 diabetes under metformin (at least 1500 mg daily) treatment. Regarding plasma homocysteine, patients were divided into two groups: 31patients with normal homocysteine (group 1: Hcy<15 µmol/L) and 39 patients with hyperhomocysteinemia (group 2: Hcy>15 µmol/L). Results: 55.1% patients had hyperhomocysteinemia but none of them had folate and B12 deficiency. Significant differences between the two groups were found for serum folate, total antioxidant capacity and creatinine. No differences were found for insulin resistance and glycemic control. Multiple stepwise linear regression analysis using plasma homocysteine as a dependent variable and all other clinical and laboratory parameters as independent variables indicated that age (β=0.344), creatinine (β=0.351), vitamin B12 (β=0.235), total antioxidant capacity (β=0.285) and malondialdehyde (β=0.245) were independently associated with homocysteine concentration. No correlation was found between the homocysteine and glycemic control, HOMA-IR and intake of B vitamins and caffeine. Conclusion: Further studies with a large sample size are required to assess the association of plasma homocysteine with total antioxidant capacity and other biomarkers of oxidative stress in type2 diabetes.


Mh Somi, at Eftekharsadat, M Masoudi, M ShirMohammadi, Sh Naghashi,
Volume 20, Issue 80 (7-2012)
Abstract

Background and Objective: Gastric cancer is a common cancer in East-Azerbaijan (Northwest of Iran). In a community with high rates of gastric cancer, dyspepsia may be a symptom of a serious problem. The main aims of this study were to evaluate the gastric mucosal changes in dyspeptic patients from Azerbaijan and to compare it with similar patients from Hormozgan (a community with low rates of gastric cancer in the South of Iran). Materials and Methods: In this analytic-descriptive setting, 191 patients with dyspepsia were evaluated at the Tabriz Liver and Gastrointestinal Diseases Research Center. Upper endoscopy was done in all patients and biopsies were obtained from 5 different points of the stomach, followed by histopathological assessments. Results: A total of 101 patients from Azerbaijan (so-called Azari)‍‍ and 90 patients from Hormozgan (so-called Bandari) were enrolled. Endoscopically determinable lesion was significantly more frequent in the patients from Hormozgan (68.3% case vs. 81.1% control x2test P=0.03). HP infection was determined in 69.3 and 84.1 percent of the patients from Azarbayjon and Hormozgan, respectively. Active chronic and chronic gastritis were found in 72.3% and 23.8% of Azari group and 73.6% and 25.3% of Bandari group. In those patients with gastritis, corpus predominant or pangastritis was more common in the Bandari group (64.1% Azari vs. 83.3% in the Bandari). Chronic gastritis (Mean scores 10.96±2.8 Bandari v 8.5 ± 3.2 Azari, P<0.001, u=2494) and active gastritis (Mean scores 7.6 ± 5.7 Bandari vs. 3.4 ± 3 Azari, P<0.001, u=2572) were severe in the Bandari group. No cases of displasia and adenocarcinoma were detected. Conclusion: Our findings show that endoscopically determinable lesion, HP infection, chronic and active chronic gastritis of gastric mucosa, and the corpus predominant or pangastritis were more common in the patients from Hormozgan.


N Najafzadeh, M Nobakht, K Mansoori, A Niapour, Mg GolMohammadi,
Volume 20, Issue 83 (8-2012)
Abstract

Background and Objective: Spinal cord injury (SCI) has a high incidence rate in the world. However, until recently, there has been no reliable treatment available for its sensory and motor complications. Utilization of stem cells has opened new insights for treatment of SCI. Hair follicle stem cells (HFSCs) are multipotent, have high proliferative potential, and easily accessible. Here, we isolated HFSCs and transplanted them to Rats with spinal cord injury by compression model. Materials and Methods: HFSCs were isolated from the bulge area of Wistar rat whisker follicles. The SCI model was induced in 14 rats, and cultivated HFSCs were transplanted to the spinal cord lesion sites. Functional recovery was assessed by Basso–Beattie–Bresnahan (BBB) scale and muscular activity changes were evaluated with electromyography (EMG) 8 weeks following the transplantation. Results: Behavioral assessments with BBB test showed that scores in transplanted animals were higher than the control group. Functional recovery in the transplanted group were better eight weeks after transplantation (p=0.023) and BBB scores were 15.64 ±0.32 compared to 12.8 ±0.45 in the sham group. Moreover, the signal amplitude of the needle EMG records of the lower extremity muscles increased in transplanted rats. Conclusion: Our results show that transplantation of HFSCs to the site of SCI could be useful for repair and replacement of degenerated neuronal and glial cells.


A Ardebili, L Azimi, H Mohammadi-Barzelighi, P Owlia, M Beheshti, M Talebi, M Jabbari, A Rastegar Lari,
Volume 20, Issue 83 (8-2012)
Abstract

Background and Objective: Acinetobacter baumannii is an important human pathogen that has been a focus of attention in recent years. These bacteria are a leading cause of therapeutic resistant nosocomial infections especially in burned or hospitalized patients in intensive care Units. The aim of this study was to isolate the Acinetobacter baumannii species from the wounds of burned patients and to determine antimicrobial resistance pattern of these bacteria for selection of appropriate antibiotics. Materials and Methods: Samples were collected from patients and transferred to the laboratory under standard conditions. Bacteria were isolated and purified by conventional culture methods. Identification of bacterial species was performed by standard biochemical tests. The isolates that were identified as Acinetobacter baumannii were subsequently tested for antibiotic resistance by the disk diffusion agar method for 17 different antibiotics. The tests were carried out on Muller Hinton agar (MHA) plates and incubated at 35˚C for 18 hrs. The minimum inhibition concentrations were determined for 5 common therapeutic antibiotics. Results: Out of the 65 clinical Acinetobacter baumannii isolates collected, 61 (94%) were multi drug resistant (MDR). Ceftazidime and aztronam (98%) were the most effective antibiotics against Acinetobacter baumannii. To determine the MIC, the highest levels of antibiotic resistance were seen against ceftazidime, cefepime, and ciprofloxacin. Conclusion: Our results confirm the high prevalence of Acinetobacter baumannii resistant isolates and the ensuing therapeutic problems in Iran. Determination of the resistance patterns of these bacteria according to MIC is necessary, and it can be especially helpful in treatment of burned patients.


R Mohammadi, M Seyedjavadi, E Mazaheri,
Volume 21, Issue 85 (4-2013)
Abstract

Background and Objective: The infant hospitalization crisis causes severe stress to the parents. The nursing staff can play an effective role in reducing the tension because of the close relationship they have with infant mothers. The main aim of this research was to determine the rate of anxiety in mothers of hospitalized infants and to determine the primary factors in order to reduce their tension. Materials and Methods: In this descriptive cross-sectional study, a total of 80 mothers were selected by convenient sampling. The questionnaire was designed based on researcher’s investigation and the pss:NICU pattern containing 8 demographic questions and 43 tension factor questions. The SPSS statistical software and descriptive and analytical statistical methods of T-test, ANOVA, and Pearson correlation were used for data analysis. Results: Our data indicates that mothers suffered a tension grade of 164.61 ±22. The highest tension score was related to the care methods with 33.37 ±7.4, and the lowest score was related to the staff behavior with 10.83 ±3. Conclusion: Our observations show that the majority of mothers face stress regardless of their demographic differences and that the highest stress factor was related to the care methods, and the lowest was related to staff behavior. Therefore, the nursing staff must be aware of the factors causing stress so that they can apply appropriate practices to decrease the complications.



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