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Showing 2 results for Mosavi Nasab

Y Shirvani, M Payami Bousari, S Kashani, Sn Mosavi Nasab,
Volume 20, Issue 81 (9-2012)
Abstract

Background and Objective: Hypoxia is a major problem in patients undergoing ventilation due to the high bronchioles secretion. This study aimed to determine the effect of expiratory rib-cage compression prior to endotracheal suctioning on arterial blood oxygenation (SpO2) in patients undergoing mechanical ventilation. Materials and Methods: This clinical trial with a crossover design included 50 mechanically ventilated patients hospitalized in the intensive care units of two educational hospitals (Vali-e-Asr and Ayatollah Mousavi) of Zanjan using the convenience sampling method. The participants were randomly divided into two groups. During the first phase of the study, the rib-cage compression was performed once for five minutes prior to suctioning in group one. The other group received suctioning without any rib-cage compression. The procedures were performed in a reverse fashion in the two groups after three hours. SpO2 was measured three times: five minutes prior to the endotracheal suctioning, and 15 and 25 minutes following the procedure. Data were analyzed using independent and paired t-tests. Results: There were statistically significant differences in the SpO2 mean values between five minutes before and 15 minutes after the endotracheal suctioning in patients who received endotracheal suctioning with the rib-cage compression (P< 0.05). Moreover, there was a statistically significant difference between the mean SpO2 values in the same intervals between the two groups (P< 0.0001). Conclusion: The results show that expiratory rib-cage compression prior to endotracheal suctioning improves arterial blood oxygenation in patients undergoing mechanical ventilation. Therefore, we recommend performing the procedure.


R Eghdam Zamiri, M Moghimi, N Mosavi Nasab, H Amirmoghadami, M Joghatae , A Feizi,
Volume 20, Issue 81 (9-2012)
Abstract

Background and Objective: Elevation of the b-HCG serum levels has been reported in several tumors including breast cancer, and it is usually associated with aggressiveness. The aim of this study was to examine the possible correlation between the b-HCG serum levels and different grades of breast cancer tumors in patients undergoing chemotherapy. Materials and Methods: This cross-sectional study was conducted in the city of Zanjan during 2009-10. Serum samples from 56 cases of breast cancer patients were collected after surgery and prior to chemotherapy for analysis of total free b-HCG by electro chemiluminescence immunoassay, and the same procedure was repeated after 8 courses of chemotherapy. The b-HCG serum levels were compared in poor versus mild to moderate grades before and after chemotherapy. Results: In 37 cases of mild to moderate grade tumors, the mean b-HCG level was 1.09 ±1.4 miu/ml compared with 1.2 ±0.3 miu/ml (P= 0.75) in 29 cases of poor grade tumors. The mean b-HCG levels before and after chemotherapy were 1.15 ±1.4 miu/ml and 1.17 ±1.4 miu/ml (P=0.24), respectively. Conclusion: We did not find any significant association between the b-HCG serum levels and breast cancer tumor grades. Furthermore, chemotherapy does not appear to have an effect on b-HCG serum levels.



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