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Volume 8, Issue 30 (3-2000)

F Ramezani Tehrani, A Moini, Ar Khalaj, M Eskandarloo,
Volume 16, Issue 63 (6-2008)

Background and Objective: This study was conducted to evaluate the clinical and reproductive outcomes after Laparoscopic Ovarian Drilling (LOD) performance in infertile women with Clomiphene resistant Poly Cystic Ovary Syndrome (PCOS). Regular menstrual cycles, ovulation and pregnancy rates have been considered as three main outcomes being evaluated in this study. Materials and Methods: 72 Clomiphene-resistant anovulatory women with PCOS in Karaj Hospital were taken into account in this study from 2002-2005. Laparoscopic Ovarian Drilling (LOD) using a needle cautery was performed. Each ovary was punctured at 6 points. Patients were followed for 24 months for evaluating the outcome. Result: After laparoscopy, regular menstruation occurred spontaneously in 82.6% and maintained regular at least for 6 months. The incidence of conception at 6, 12, 18, and 24 months after surgery was % 14.7, %36.8, %58.5, %67.6 respectively. Conclusion: Laparoscopic ovarian drilling is an effective treatment in Clomiphene-resistant anovulatory women with PCOS.

F Sadeghi, M Khalaj-Kondori, Ma Hosseinpour Feizi, F Shaikhzadeh Hesari,
Volume 22, Issue 95 (8-2014)

Background and Objective: Learning is the acquisition of information about the world and memory is a mechanism to encode, store and retrieve the learned information. Weak memory and learning disorders are the most common cognitive problems. In the present study, the pharmacological effects of aqueous extract of Boswellia on learning and spatial memory in male rats was investigated using the Morris water maze (MWM) test. Materials and Methods: In this experimental study, 21 male rats were divided into 3 groups including a control group (distilled water) and two groups treated with aqueous extract of Boswellia (50 and 100 mg/kg) that received the treatment for 4 weeks. To evaluate learning ability of animals, Morris Water Maze was used. Results: In the first and the last day of training, all groups showed significant reduction in escape latency (P<0.0001) and traveled distance (P<0.0001). In the sixth day of training, both treatment groups showed significant reduction in escape latency (P<0.05) and traveled distance (P<0.05) in comparison with the control group. Conclusion: The results suggest that intake of Boswellia facilitates the learning and spatial memory formation in rats via Morris water maze test method. References 1- Sharifzadeh M, Sharifzadeh K, Naghdi N, Ghahremani MH, Roghani A. Posttraining intrahippocampal infusion of a protein kinase AII inhibitor impairs spatial memory retention in rats. J Neurosci Res. 2005 79(3): 392-400 2- Francis PT, Palmer AM, Snape M, Wilcock GK. The cholinergic hypothesis of Alzheimer’s disease: a review of progress. J Neurol Neurosurg Psychiatry. 1999 66(2): 137-47. 3- Abdel-Tawab M WO, Schubert-Zsilavecz M. Boswellia serrata: an overall assessment of in vitro, preclinical, pharmacokinetic and clinical data. Clin Pharmacokinet. 2011 50(6): 349-69. 4- Hussain H, Al-Harrasi A, Al-Rawahi A, Hussain J. 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